“Fire crews from Islington, Soho, Kentish Town, Stoke Newington, Lambeth and surrounding fire stations are at the scene.”
He added the cause of the fire is under investigation.
There have been no reported deaths or injuries at this stage.
The pub is understood to be close to Kings Cross and St Pancras stations.
“Caledonian Road has been closed between Pentonville Road and Caledonian Street”
London Fire Brigade spokesman
LFB later said crews were “making steady progress” in battling the fire.
It comes after fire crews in Birmingham tackled a blaze on a bus.
Firefighters were seen trying to hose down the double-decker bus, which appeared to have its roof blown off.
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